Pathology and therapeutics for pharmacists : a basis for clinical pharmacy practice / Russell J. Greene and Norman D. Harris

Includes index.

Table of contents. – Ch. 1 Basic strategy and introduction to pathology - - Therapeutics: general strategy - - Terminology of disease - - Case history - - Drug disposition - - Drug selection - - Ischaemia - - Major pathological processes in disease - - Immunology - - Inflammation - - Body systems and their principal diseases - - Gastrointestinal and liver diseases - - Gastrointestinal anatomy and physiology - - Investigation - - Disorders of the upper gastrointestinal tract - - Oesophageal disorders - - Helicobacter infection and gastroduodenal disease Dyspepsia - - Peptic ulcer disease - - Nausea and vomiting - - Problems of the small and large intestine - - Malabsorption - - Inflammatory bowel disease - - Other colonic and rectal disorders - - Stomatherapy - - Liver diseases - - Clinical physiology of the liver - - Clinical features of hepatic disease Gallstones (cholelithiasis) - - Liver failure - - Viral and other infective hepatitis - - Drugs and the liver - - Cardiovascular system - - Physiological principles of the cardiovascular system Clinical - - features of cardiovascular disease Heart failure - - Hypertension - - Ischaemic heart disease - - Atherosclerosis and vascular - - obstructive disease - - Acute coronary syndrome - - Summary of cardiovascular aetiologies - - Respiratory diseases - - Anatomy and clinical physiology of the respiratory system - - Clinical aspects of respiratory disease - - Obstructive pulmonary disease - - Asthma - - Other allergic lung diseases - - Chronic obstructive pulmonary disease - - Restrictive lung disease - -Diseases of the pulmonary circulation Respiratory failure Inhalation therapy - - Oxygen therapy - - Central nervous system Physiological principles 366 Psychiatric disorder - - Clinical aspects of psychiatric disorder - - Anxiety - - Affective disorder: depression - - Mania and manic-depressive disorder - - Schizophrenia - - Neurological disorder - - Parkinson's disease and the extrapyramidal syndromes - - Epilepsy - - Pain and its treatment Introduction - - Pathophysiology of pain - - Principles of analgesic use - - Analgesic drugs and techniques - - Opioid analgesics - - Less potent analgesics - - Analgesic adjuvants - - Other methods of pain control - - Local anaesthetics - - Topical agents - - Physical methods - - Techniques recruiting endogenous inhibitory mechanisms - - Chemical nerve blocks - - Neurosurgical approaches - - Psychotherapy and hypnosis - - Syringe drivers and patient-controlled analgesia - - Some common pain situations - - Headache, migraine and facial pain - - Post-herpetic neuralgia - - Some special pain situations - - References and further reading Infections and antimicrobial therapy Introduction - - Classification of microorganisms - - Classification and properties of antimicrobials - -Penicillins - - Cephalosporins - - Aminoglycosides - - Other antimicrobial agents - - Antifungal agents - - Antiviral agents - - Therapeutic decisions in antimicrobial therapy - - Some important infections - - References and further reading - - Endocrine system Diabetes mellitus - - Physiological principles of glucose and insulin metabolism Epidemiology and classification - - Aetiology and pathogenesis - - Natural history - - Clinical features - - Complications - - Management - - Monitoring - - Thyroid disease - - Physiological principles - - Hypothyroidism - - Hyperthyroidism - - Neoplastic disease - - Classification and epidemiology of cancer - - Aetiology - - Pathobiology - - Cytokinetics - - Clinical features - -
Investigation and diagnosis - - Management: aims and strategy - - Cytotoxic chemotherapy - - Endocrine therapy - - Other pharmacotherapy - - Rational design of antineoplastic regimens - - Haematology
Red blood cell production and function - - Anaemia Neutropenia and agranulocytosis - - Haemostasis, fibrinolysis and anticoagulation - - Rheumatology: musculoskeletal and connective tissue diseases - - Anatomy and physiological principles of the musculoskeletal system - - The immune system and rheumatic diseases - - Examination, investigation and assessment - - Principal arthritic diseases - - Osteoarthritis - - Rheumatoid arthritis - - Seronegative spondarthritides - - Ankylosing spondylitis - - Crystal deposition arthropathies - - Common features and pathology - - Gout - - Pyrophosphate arthropathy - - Autoimmune connective tissue disorders - - Systemic lupus erythematosus - - Sjögren's syndrome (keratoconjunctivitis sicca)- - Systemic sclerosis and scleroderma - - Raynaud's syndrome Vasculitides - - Other multisystem diseases - - Other rheumatic disorders - - Reactive arthritis - - Soft tissue rheumatism - - Skin diseases - - Skin anatomy and physiology - - Clinical features of skin diseases - - General management of skin diseases - - Psoriasis - - Eczema and dermatitis - - Acne - - Rosacea - - Urticaria - - Drug-induced skin disease - - The skin as a route for systemic drug delivery - - Renal system - - Physiological principles of the renal system - - Clinical features and investigation of renal disease - - Renal failure - - Renal replacement therapy - - Important renal diseases.